Biomarkers for a better understanding of Alzheimer’s
The project analyzes proteins related to the central nervous system in people with Alzheimer’s and in healthy individuals, also comparing how these indicators vary according to biological sex.
Paragraph: This line of work stems from a relevant reality: Alzheimer’s affects both women and men, but there are differences that science still needs to understand better.
Why it matters
Questions that help guide research
Paragraph: Studying these proteins allows for the exploration of altered mechanisms, the identification of patterns, and progress toward a more precise understanding of the disease.
The goal is not to promise immediate answers, but to generate useful knowledge to guide new lines of research, prevention, and more personalized medicine.
Differences between women and men
Initial results show many similarities between women and men, but also specific differences, especially in proteins related to the immune system and inflammation.
Genetics and risk
The project also considers genetic variables, such as the APOE genotype, to better understand their relationship with biomarkers and the development of the disease.
New lines of research
POLARIS helps identify scientific questions with the potential to guide future studies against Alzheimer’s.
Scientific team
A project led by leading figures in neurology and research
The project is led by Dr. Raquel Sánchez-Valle and the team from Clínic Barcelona-IDIBAPS, with a solid track record in research, neurology, and cognitive disorders.
Collaboration with a leading scientific center allows FRMV to channel private resources into specific research, with monitoring, rigor, and the ability to communicate progress.
Results and traceability
Private resources for verifiable research
POLARIS already has initial results and a publication in Alzheimer’s Research. For FRMV, this project demonstrates that private collaboration can be transformed into verifiable scientific research.
Paragraph: This model sets a line of work for future initiatives: identifying relevant projects, mobilizing resources, monitoring progress, and bringing the knowledge generated closer to society.